How Do Nsaids Cause A Peptic Ulcer
To understand how NSAIDs cause peptic ulcer disease, it is important to understand how NSAIDs work. Nonsteroidal anti-inflammatory drugs reduce pain, fever, and inflammation, or swelling.
Everyone has two enzymes that produce chemicals in your bodys cells that promote pain, inflammation, and fever. NSAIDs work by blocking or reducing the amount of these enzymes that your body makes. However, one of the enzymes also produces another type of chemical that protects the stomach lining from stomach acid and helps control bleeding. When NSAIDs block or reduce the amount of this enzyme in your body, they also increase your chance of developing a peptic ulcer.
What Are The Symptoms Of A Peptic Ulcer Does It Cause Pain
Ulcers do not always cause symptoms. Sometimes, a serious complication such as bleeding or a sudden, bad upper abdominal pain is the first sign of an ulcer.
The most common symptom of peptic ulcers is abdominal pain.
- The pain is usually in the upper middle part of the abdomen, above the belly button and below the breastbone.
- The ulcer pain can feel like burning, or gnawing, and it may go through to the back.
- Pain often comes several hours after a meal when the stomach is empty.
- The pain is often worse at night and early morning.
- It can last anywhere from a few minutes to several hours.
- The ulcer pain may be relieved by food, antacids, or vomiting.
Other symptoms of peptic ulcers include the following:
- Loss of appetite
- Loss of weight
Severe ulcers may cause bleeding in the stomach or duodenum. Bleeding is sometimes the only symptom of an ulcer. This bleeding can be fast or slow. Fast bleeding reveals itself in one of the following ways:
- Vomiting of blood or dark material that looks something like coffee grounds: This is an emergency and warrants an immediate visit to an emergency department.
- Blood in the stool or black, tarry, sticky-looking stools
Slow bleeding is often more difficult to detect, because it has no dramatic symptoms.
- The usual result is low blood cell count .
- The symptoms of anemia are tiredness , lack of energy , weakness, rapid heartbeat , and pale skin .
Other Causes And Factors
Other causes are rare. For example, some viral infections can cause a stomach ulcer. Crohn’s disease may cause a stomach ulcer in addition to other problems of the gut.
Stomach cancer may at first look similar to an ulcer. Stomach cancer is uncommon but may need to be ‘ruled out’ if you are found to have a stomach ulcer.
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What Should I Watch For While Using This Medicine
Do not smoke cigarettes or drink alcohol. These increase irritation to your stomach and can make it more susceptible to damage from medicine like ibuprofen and aspirin.
If you are female, do not use this medicine if you are pregnant. Do not get pregnant while taking this medicine and for at least one month after stopping this medicine. If you can become pregnant, use a reliable form of birth control while taking this medicine. Talk to your doctor about birth control options. If you do become pregnant, think you are pregnant, or want to become pregnant, immediately call your doctor for advice.
Is There A Peptic Ulcer Diet Plan
No particular diet is helpful for people with peptic ulcers. At one time, a bland diet and avoidance of spicy or greasy foods was recommended. Milk and dairy food have been used in the past for ulcer symptoms, but have not been proven to be effective. We now know diet has little effect on ulcers. In some people, however, certain foods seem to aggravate stomach ulcer symptoms. Keep a food diary with your intake and the resulting symptoms and avoid eating any foods that aggravate symptoms.
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When Should I See A Doctor If I Think I Have A Peptic Ulcer
- If you have burning pain in your upper stomach that is relieved by eating or taking antacids, call a health-care professional for an appointment. Dont assume you have an ulcer. Certain other conditions can cause similar symptoms.
- If you vomit blood or have other signs of gastrointestinal bleeding, go to an emergency department right away. Peptic ulcers can cause massive bleeding, which requires blood transfusion or surgery.
- Severe abdominal pain suggests perforation or tearing of an ulcer. This is an emergency that may require surgery to fix a hole in your stomach.
- Vomiting and abdominal pain also can be a sign of an obstruction, another complication of peptic ulcers. This also may require emergency surgery.
What Is Peptic Ulcer Disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the lining of the stomach or the first part of the small intestine . Normally, a thick layer of mucus protects the stomach lining from the effect of its digestive juices. But many things can reduce this protective layer, allowing stomach acid to damage the tissue.
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When Should I Call My Healthcare Provider
See your healthcare provider right away if you have any of these symptoms:
- Vomiting blood or dark material that looks like coffee grounds
- Extreme weakness or dizziness
- Blood in your stools
- Nausea or vomiting that doesnt get better, or gets worse
- A sudden, severe pain that may spread to your back
- Losing weight without even trying
Untreated peptic ulcers may cause other health problems. Sometimes they bleed. If they become too deep, they can break through your stomach.
Ulcers can also keep food from going through your stomach.
How Soon After Treatment Will I Feel Better
If you take all medicines as prescribed and avoid irritating the ulcer with NSAIDs, alcohol or smoking, your ulcer should heal well within a few weeks. Surgical cases may take a few weeks more. Your healthcare provider will follow up with you at the end of your course of medication to make sure the ulcer has healed and any infection has cleared. They will probably take follow-up tests, including an upper endoscopy to look at the site of the ulcer and tests for H. pylori, if you had it, to make sure the infection is gone.
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Signs You May Have A Stomach Ulcer
We have absolutely warned our patients about the dangers of untreated ulcers in the past. However, we consider this to be an extremely important matter and therefore, we will continue to try to educate the people of Los Angeles, as well as those elsewhere on the most common symptoms of stomach ulcers. If you know the signs, you can see your doctor sooner rather than later when things have gotten especially bad. Continue reading below to get familiar with what these symptoms are.
Treatment For A Stomach Ulcer
Special diets are now known to have very little impact on the prevention or treatment of stomach ulcers. Treatment options can include:
- medication including antibiotics, to destroy the H. pylori colony, and drugs to help speed the healing process. Different drugs need to be used in combination some of the side effects can include diarrhoea and rashes. Resistance to some of these antibiotics is becoming more common
- subsequent breath tests used to make sure the H. pylori infection has been treated successfully
- changes to existing medication the doses of arthritis medication, aspirin or other anti-inflammatory medication can be altered slightly to reduce their contributing effects on the stomach ulcer.
- reducing acid tablets are available to reduce the acid content in the gastric juices
- lifestyle modifications including quitting cigarettes, since smoking reduces the natural defences in the stomach and impairs the healing process.
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Is Cheese Bad For Stomach Ulcers
Low-fat dairy Low-fat or fat-free milk, yogurt, and mildly flavored cheeses, such as cottage cheese, are all good options. Be careful, though. Lactose intolerance and milk protein intolerance are common reasons for GI discomfort in some people. And many experts recommend eliminating dairy to help treat peptic ulcers.
What Are The Symptoms Of Stomach And Duodenal Ulcers In A Child
Ulcers dont always cause symptoms.
The most common symptom is a gnawing or burning pain in the stomach. This is often felt between the breastbone and the belly button . Your child may feel the pain more between meals and in the early morning. It may last from a few minutes to a few hours.
Less common ulcer symptoms include:
Tiredness and weakness
The symptoms of ulcers may look like other health problems. Make sure your child sees his or her healthcare provider for a diagnosis.
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Signs You May Have An Ulcer
Did you know that stomach ulcers also called peptic ulcers affect at least 1 in 10 Americans over the course of their lives? And while stomach ulcers can be treated easily when caught early, lack of medical care can lead to serious complications.
Understanding the signs of stomach ulcers is important in helping you get the treatment you need. At Prima Medicine in Fairfax and South Riding, Virginia, our care team has the experience and knowledge to diagnose and treat stomach ulcers. Weve curated this guide to help you recognize the warning signs of an ulcer and understand what you can do about it.
Can Stomach Ulcers Be Treated
Yes, stomach ulcers can heal well with a medication regimen. The type of treatment will depend on what caused your ulcer.
If your stomach ulcer was caused by a H. pylori bacterial infection, youll likely receive antibiotics and a proton pump inhibitor medication. The antibiotics could include:
The PPIs that you will also be prescribed will block the production of stomach acid. There are both prescription and over-the-counter PPI medications, including:
You may also end up taking histamine blockers, or H-2 blockers, that reduce the stomach acid released into your digestive tract. The reduction of stomach acid can promote healing and lessens the pain you may be feeling. Your doctor may prescribe these or you could take over-the-counter medications such as:
- Axid AR
- Pepcid AC
- Tagamet HB
Your doctor may also prescribe antacids to help with symptom relief. There are also medications called cytoprotective agents to protect the lining of your stomach, such as Carafate and Cytotec .
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Foods To Limit When You Have Acid Reflux And An Ulcer
Some people who have an ulcer also have acid reflux. In some people, certain foods can relax the lower part of the esophagus, known as the lower esophageal sphincter or LES. A relaxed LES makes it easier for acid to back up into the esophagus and cause heartburn, indigestion, and pain.
Foods that may make acid reflux worse include:
What Is Massive Upper Gastrointestinal Bleeding
Upper GI bleeds occur when part of the upper digestive tract becomes injured or inflamed. A GI bleed is a symptom of another disorder rather than a health condition in itself. Doctors divide GI bleeds into upper and lower bleeds depending on the source of the blood. Upper GI bleeds can occur in the: esophagus.
Call your GP immediately or go to the emergency department if:
- you have symptoms of severe bleeding
In the hospital, a doctor will do an endoscopy to identify the cause of the bleeding. They can give you treatment during the endoscopy to stop the bleeding.
Your doctor may do a specialised procedure with x-ray guidance to stop a bleeding ulcer. In rare cases, you may need surgery to repair the affected blood vessel.
You may also need blood transfusions to replace the blood you have lost.
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If Your Ulcer Was Caused By Helicobacter Pylori
Most stomach ulcers are caused by infection with H. pylori. Therefore, a main part of the treatment is to clear this infection. If this infection is not cleared, the ulcer is likely to return once you stop taking acid-suppressing medication. For more information, see the separate leaflet called Helicobacter Pylori.
What Triggers Stomach Ulcer Symptoms
Stomach ulcers are irritated by stomach acid. Some people notice this irritation more after they eat, and some people notice it more on an empty stomach. There are also certain irritants that seem to make ulcer symptoms worse and make them more difficult to heal. Smoking and alcohol are the biggest ones.
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How Are Stomach Ulcers Treated
Ulcers can heal if they are given a rest from the factors that created them. Healthcare providers treat uncomplicated ulcers with a combination of medicines to reduce stomach acid, coat and protect the ulcer during healing and kill any bacterial infection that may be involved. Medicines may include:
- Antibiotics. If H. pylori was found in your digestive tract, your healthcare provider will prescribe some combination of antibiotics to kill the bacteria, based on your medical history and condition. Commonly prescribed antibiotics include tetracycline, metronidazole, clarithromycin and amoxicillin.
- Proton pump inhibitors . These drugs help reduce stomach acid and protect your stomach lining. PPIs include esomeprazole,dexlansoprazole,lansoprazole, omeprazole,pantoprazole and rabeprazole.
- Histamine receptor blockers . These reduce stomach acid by blocking the chemical that tells your body to produce it . H2 blockers include famotidine, cimetidine and nizatidine.
- Antacids. These common over-the-counter medicines help to neutralize stomach acid. They may bring some symptom relief, but they arent enough to heal your ulcer. They also might interfere with some antibiotics.
- Cytoprotective agents. These medicines help to coat and protect your stomach lining. They include sucralfate and misoprostol.
- Bismuth Subsalicylate. This over-the-counter medicine, commonly found as Pepto-Bismol, can help coat and protect your ulcer from stomach acid.
How Are Stomach Ulcers Diagnosed
Diagnosis and treatment will depend on your symptoms and the severity of your ulcer. To diagnose a stomach ulcer, your doctor will review your medical history along with your symptoms and any prescription or over-the-counter medications youre taking.
To rule out H. pylori infection, a blood, stool, or breath test may be ordered. With a breath test, youll be instructed to drink a clear liquid and breathe into a bag, which is then sealed. If H. pylori is present, the breath sample will contain higher-than-normal levels of carbon dioxide.
Other tests and procedures used to diagnose stomach ulcers include:
- Barium swallow: You drink a thick white liquid that coats your upper gastrointestinal tract and helps your doctor see your stomach and small intestine on X-rays.
- Endoscopy : A thin, lighted tube is inserted through your mouth and into the stomach and the first part of the small intestine. This test is used to look for ulcers, bleeding, and any tissue that looks abnormal.
- Endoscopic biopsy: A piece of stomach tissue is removed so it can be analyzed in a lab.
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How A Stomach Ulcer Is Treated
If youre experiencing a stomach ulcer, your health care provider may refer you to a gastroenterologist, a health care specialist who is specialty-trained in conditions affecting the GI system, including the stomach.
To confirm a diagnosis and help determine a treatment plan, he or she may perform a breath test to detect the presence of pylori bacteria. Blood tests and stool tests can also be used for the same purpose.
If a stomach ulcer is untreated, it can worsen and perforate. Its important to seek a diagnosis and treatment plan to properly alleviate your symptoms.
How long do stomach ulcers last? That depends on multiple factors, including the underlying cause of your ulcer. If you have a stomach ulcer caused by Helicobacter pylori, youll be given an antibiotic to rid your body of the bacteria. Youll typically be told to take the medication for two to three weeks to fully clear the pylori bacteria from your system. Depending on the severity of the infection, you may even be prescribed a combination of antibiotics.
In addition, to ease the symptoms associated with the ulcer and allow the stomach to heal, your doctor will also likely prescribe a protein pump inhibitor or other similar medication to reduce the amount of acid in your stomach.
Key Points About Stomach And Duodenal Ulcers In Children
Stomach and duodenal ulcers are open sores. They happen in the lining of the stomach or the duodenum.
Most ulcers are caused by an infection with Helicobacter pylori.
Treatment often includes antibiotics and medicines to block stomach acid production.
Without proper treatment, people with ulcers may have serious complications. But most people are cured with treatment.
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What Causes Stomach Ulcers
The two most common causes are:
- H. pylori infection. This common bacterial infection affects up to half of people worldwide. It primarily lives in the stomach. In many people, it doesnt seem to cause problems. Their gut immune systems keep it in check. But a portion of those infected have H. pylori overgrowth. The bacteria continue to multiply, eating into the stomach lining and causing chronic inflammation and peptic ulcer disease. H. pylori infection is associated with about 60% of duodenal ulcers and 40% of gastric ulcers.
- Overuse of NSAIDs. NSAID stands for non-steroidal anti-inflammatory drug.” These include common over-the-counter pain relief medications such as ibuprofen, naproxen and aspirin. NSAIDs contribute to ulcers in several ways. They irritate the stomach lining on contact and repress some of the chemicals that defend and repair the mucous lining. Up to 30% of people who take NSAIDs regularly develop peptic ulcers. Up to 50% of all peptic ulcers are caused by the overuse of NSAIDs.
Less common causes of stomach ulcers include:
- Zollinger-Ellison Syndrome. This is a rare condition that causes your stomach to produce too much gastric acid.
- Severe physiological stress. Severe illness, burns or injuries can produce stress ulcers in the stomach. Physiological stress changes your bodys PH balance, increasing stomach acid. Stress ulcers develop very quickly in response to stress, unlike normal stomach ulcers that develop gradually.