Research On The Prevention Of Peptic Ulcers
A group of researchers from the an international network of researchers wanted to find out which medications can prevent the development of peptic ulcers. To do so, they looked for studies where NSAIDs were combined with PPIs, H2 blockers or misoprostol. The researchers found 41 suitable studies with a total of more than 21,000 participants.
The people in the studies were mainly men and women who had osteoarthritis or a rheumatic disease. All of them took one or several NSAIDs for at least three weeks and had a fairly high risk of getting a peptic ulcer. A number of the studies compared proton pump inhibitors, H2 blockers or misoprostol with a placebo or with each other. The participants were observed for up to one year. Regardless of whether they had symptoms, in almost all of the studies the participants had a gastroscopy to see whether they had an ulcer in their stomach or duodenum.
If You Suffer From Ulcers Here’s The Life
Ulcers can react badly to over-the-counter medicine and could prove fatal. Here’s all the information you need to know.
If you have an ulcer, you need to avoid any foods or medicines that will make your condition worse Before you reach for the painkillers next time you are in pain, make sure you read this first.
Painkillers work by blocking the effects of these pain chemicals. The problem is that you can’t focus most pain relievers specifically on your headache or bad back. Instead, it travels through your whole body. This can cause some unexpected side effects.
The same chemicals that amplify pain, which some pain medicines block, also help maintain the protective lining of the stomach and intestines. When a painkiller stops these chemicals from working, the digestive tract becomes more vulnerable to damage from gastric acids.
Making A Decision And Considering Alternative Options
All three types of stomach-protecting medication can lower the risk of getting peptic ulcers. Proton pump inhibitors and H2 blockers appear to be very well tolerated. But it is important to make sure the dose of H2 blockers is high enough. H2 blockers can become less effective over time because your body gets used to them. This doesn’t seem to be a problem when taking proton pump inhibitors.
The risk of stomach and bowel problems can be reduced by taking the lowest possible dose of painkillers, and only taking them for as long as necessary. Acetaminophen may sometimes be an alternative to NSAIDs. It doesn’t increase the risk of peptic ulcers and is often just as effective. But it has side effects too: For instance, it may cause liver damage if the dose is too high or if you take it regularly.
It’s best to talk to a doctor about how high your own personal risk of getting a peptic ulcer is, as well as what medications you could take to protect your stomach.
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Symptoms Of Peptic Ulcer Disease
The most common symptom is a burning pain in your stomach. It usually lasts for a few minutes to a few hours. It comes and goes for days or weeks at a time. The burning typically occurs between meals and at night. Small ulcers may cause no symptoms.
Other symptoms can include:
- Difficulty drinking as much liquid as usual
- Hunger or an empty feeling in your stomach after you eat
Continue Learning About Ulcer Treatment
Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.
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Complications Of Peptic Ulcers
Left untreated, peptic ulcers can result in severe complications and emergencies.
- Internal bleeding You can have bleeding in your stomach, esophagus, or duodenum when the ulcer opens a blood vessel. Ulcers can cause bleeding that occurs slowly over time or quickly, possibly resulting in hemorrhaging that can be life-threatening due to shock. Sometimes you may not notice a bleeding ulcer until you become anemic, a condition in which your body lacks red blood cells because of inadequate iron. This occurs when ulcers cause chronic, low-grade blood loss.
- A hole, or perforation, in the stomach wall You can develop a perforated ulcer, which means it has eaten through your stomach or intestinal wall.
- Obstruction This is when you have swelling or scarring related to your ulcer that is preventing your food from being digested properly.
The signs that you are having an ulcer emergency are:
- Blood in vomit or vomit that looks like coffee grounds
- Increasing pain
- Mental confusion
- Severe abdominal distension
If you think you or someone you know is having an ulcer emergency, seek immediate medical attention.
Treating The Causes Of Peptic Ulcers
Doctors treat the underlying causes of peptic ulcers to help the ulcers heal and prevent them from coming back.
Helicobacter pylori infection
Doctors treat H. pylori infection with a combination of medicines. These medicines most often include
- two or more antibiotics
- in some cases, bismuth subsalicylate
Your doctor may avoid prescribing antibiotics youve taken in the past because the H. pylori bacteria may have developed antibiotic resistance to those antibiotics.
If you are given medicines, take all doses exactly as your doctor prescribes. If you stop taking your medicine early, some bacteria may survive and persist in your stomach. In other words, H. pylori bacteria may develop antibiotic resistance.
To find out if the medicines worked, your health care professional may recommend testing you for H. pylori at least 4 weeks after youve finished taking the antibiotics.2 If you still have an H. pylori infection, your doctor may prescribe a different combination of antibiotics and other medicines to treat the infection. Making sure that all of the H. pylori bacteria have been killed is important.
Nonsteroidal anti-inflammatory drugs
If you have a peptic ulcer caused by taking NSAIDs, your doctor may recommend changing your medicines. Depending on the reason you have been taking NSAIDs, your doctor may suggest stopping NSAIDs, taking a different NSAID, taking a lower-dose NSAID, or taking a different medicine for pain.
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When To See A Healthcare Provider
You may feel relief with an antacid, but you should not ignore symptoms of a peptic ulcer. If you have persistent symptoms for longer than a week, it is best to see your healthcare provider. They will determine whether you need prescription medications and whether you have complications, such as bleeding or anemia.
Make an appointment with your healthcare provider if you have:
- Pain that radiates to the back
- Pain that doesnt go away when you take medication
- Unintended weight loss
- Sudden, severe pain in the abdominal area
- Loss of consciousness
How To Treat A Peptic Ulcer
Treatment will depend on the underlying cause of your ulcer. If tests show that you have an H. pylori infection, your doctor will prescribe a combination of medication. Youll have to take the medications for up to two weeks. The medications include antibiotics to help kill infections and proton pump inhibitors to help reduce stomach acid.
You may experience minor side effects like diarrhea or an upset stomach from antibiotic regimens. If these side effects cause significant discomfort or dont get better over time, talk to your doctor.
If your doctor determines that you dont have an H. pylori infection, they may recommend a prescription or over-the-counter PPI for up to eight weeks to reduce stomach acid and help your ulcer heal.
Acid blockers like famotidine can also reduce stomach acid and ulcer pain. These medications are available as a prescription and also over the counter in lower doses.
Your doctor may also prescribe sucralfate which will coat your stomach and reduce symptoms of peptic ulcers.
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How I Do I Know If My Wind Burping Flatulence And Bloating Is Normal
The average person breaks wind up to 40 times a day. Anything less than this is normal. Often people believe that they have excessive flatus is because an embarrassing incident like a loud or smelly fart in public has led to the belief that something is wrong. However, if these events are severe, ongoing, troublesome or if you are worried about them you should discuss your concerns with your doctor.
In addition, if you develop burping associated with chest discomfort, especially discomfort associated with exertion, or if you have difficulties in swallowing you should seek medical advice.
If bloating is persistent or associated with weight loss, abdominal pain or diarrhoea you should see your doctor as it can be a symptoms of more serious bowel conditions.
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When To Seek Urgent Medical Advice
A number of symptoms can develop if a peptic ulcer suddenly causes serious complications, such as internal bleeding. These include:
- Vomiting blood – the blood can appear bright red, or have a darker, grainy appearance similar to coffee granules,
- Passing stools – which are very dark in colour or ‘tar-like’, and
- A sudden, sharp pain in your abdomen that gets steadily worse
If you experience any of the symptoms that are listed above, you should contact your GP immediately.
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What Is An Ulcer
Ulcers are open sores on the inner lining of the lower esophagus, stomach, or the upper portion of the small intestine. They are often painful, particularly after eating, and can bleed into the stomach or intestines.
Ulcers are identified by the location of the sore:
- Esophageal ulcers occur on the lower part of the esophagus, the muscular tube that connects the throat to the stomach.
- Gastric ulcers form in the stomach lining.
- Duodenal ulcers form in the lining of the small intestine near the stomach called the duodenum.
Esophageal, gastric, and duodenal ulcers are collectively called peptic ulcers or peptic ulcer disease . They are closely related both in causes and treatments. Compared to gastric and duodenal ulcers, esophageal ulcers may arise from different causes and require different treatments in some cases.
Peptic ulcers are due to an erosion of the defenses the stomach or intestinal tissues use to protect themselves against harmful stomach acid. When these defenses are compromised, the acid can eat away at the lining of the stomach or duodenum, causing sores.
Lifestyle factors, such as eating spicy foods or stress, are no longer considered risk factors for developing peptic or esophageal ulcers, but they may worsen ulcer symptoms.
Peptic ulcer disease is very common. Anywhere from 5% to 10% of the population will develop a peptic ulcer at some time during their lives. About 2% to 7% will experience an esophageal ulcer in their lifetime, mostly due to GERD.
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Bleeding Ulcers Symptoms And Causes
Bleeding ulcers are a big deal. Often having endoscopy is diagnostic and therapeutic. A gastroenterologist can use a fiberoptic camera to view the inside of the stomach and duodenum, searching for a source of bleeding.
Symptoms of a bleeding ulcer include:
- Abdominal discomfort after eating
- Upper abdominal burning or hunger pain 1 to 3 hours after eating or in the middle of the night
Why Tylenol May Be A Better Choice
- #1 Doctor Recommended Pain Relief brand for those with stomach problems.
- TYLENOL® will not irritate the stomach the way naproxen sodium , or even Ibuprofen can.
- TYLENOL® can help relieve your pain while being gentle on your stomach.
- TYLENOL® can be taken on an empty stomach.
- TYLENOL® may be a safe over the counter pain reliever for those with a history of stomach bleeding, stomach ulcers, or stomach problems such as heartburn.
- TYLENOL® is not an NSAID. NSAIDs can cause stomach ulcers and an increased risk of severe stomach bleeding.
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What To Expect During An Appendectomy
Before your appendix is taken out, youÃ¢ll take antibiotics to fight infection. YouÃ¢ll usually get general anesthesia, meaning youÃ¢ll be asleep for the procedure. The doctor removes your appendix through a 4-inch-long cut or with a device called a laparoscope . This procedure is called laparoscopy. If you have peritonitis, the surgeon will also clean out your belly and drain the pus.
You can get up and move around within 12 hours after surgery. You should be able to go back to your normal routine in 2 to 3 weeks. If you had a laparoscopy, recovery is faster.
After an appendectomy, call your doctor if you have:
- Uncontrolled vomiting
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What Are The Symptoms Of A Peptic Ulcer
A dull or burning pain in your stomach is the most common symptom of a peptic ulcer. You may feel the pain anywhere between your belly button and breastbone. The pain most often
- happens when your stomach is emptysuch as between meals or during the night
- stops briefly if you eat or if you take antacids
- lasts for minutes to hours
- comes and goes for several days, weeks, or months
Less common symptoms may include
- feeling sick to your stomach
Even if your symptoms are mild, you may have a peptic ulcer. You should see your doctor to talk about your symptoms. Without treatment, your peptic ulcer can get worse.
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How Do Ulcers Develop
NSAID usage isnt the only reason ulcers develop in the stomach or upper area of the small intestine. Another common culprit is a bacterial infection caused by Helicobacter pylori, or H. pylori. And although NSAIDs and H. pylori infection are independent risk factors, Staller said, they can work together to increase a persons chances of developing ulcers.
Dingells case appears to be more directly tied to taking ibuprofen, however. The saga, as she calls it, started months ago, when a bothersome dental implant led to a bone infection in her jaw. After she had jaw surgery in January, the lawmaker, who has been outspoken about the dangers of opioids and narcotics, instead opted to take Motrin for pain relief.
Soon, Dingell said, she was regularly downing 800 mg morning and night, which continued long after the initial surgery. By around March, Dingell said, her doctors started to raise concerns about how much ibuprofen she was taking.
The doctors warned me, she said. They told me that taking it for this long, they wanted to watch me closely, and I thought I was invincible.
Ibuprofen and other pain relievers such as naproxen, or Aleve, reduce your bodys ability to make a layer of mucus that protects the lining of your stomach from gastric acid, said Christian Stevoff, clinical practice director in the division of gastroenterology at Northwestern Universitys Feinberg School of Medicine.
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Can Stomach Ulcers Just Go Away
Some ulcers follow a chronic pattern of healing temporarily on their own and then returning. This might happen if the factors contributing to your ulcer, such as NSAID use, smoking and alcohol, are temporarily reduced and then resumed. You wont completely heal your ulcer until you eliminate the cause, whether that is chronic NSAID use, H. pylori infection or an overactive stomach. Even after successful treatment, you can get another ulcer.